Calciphylaxis: Severe Calcification of the Arteries

Treatment of Severe Metastatic Calcification and Calciphylaxis in Dialysis Patients

Metastatic calcification is a frequent complication encountered in patients undergoing maintenance dialysis and has a complex pathogenesis. It is often difficult to treat and is associated with high morbidity and mortality. Early recognition and prompt initiation of treatment is vital. Local wound care and aggressive metabolic control remain the cornerstones of the therapy. Various novel treatm...

Calciphylaxis with extensive arterial calcification

Calciphylaxis is a clinical syndrome of arteriolar calcification with resultant tissue necrosis, most commonly seen in patients with end-stage renal disease (ESRD) on dialysis. This condition carries a high mortality rate mainly due to infection. Helpful interventions include adequate dialytic therapy, medical management of hyperparathyroidism, hyperphosphatemia, and intravenous sodium thiosulf...

Perieccrine and pericapillary calcification in calciphylaxis

*Corresponding author: Jeong Hee Cho-Vega, MD, PhD, Department of Pathology, Dermatopathology Division, Miami, USA, Email: [email protected] A 44-year-old Hispanic man presented with painful feet and penis. The past medical history was notable for end-stage renal disease, type 2 diabetes mellitus, hypertension, and peripheral vascular disease. The patient was on peritoneal dialysis. Medicati...

Regression of vascular calcification in a patient with calciphylaxis.

Tumour Calcification and Calciphylaxis in End-Stage Renal Disease

Although soft tissue and vascular calcifications are common in CKD and progress as an independent risk factor of all-cause mortality, tumour calcification and calciphylaxis are uncommon in patients with end-stage renal disease (ESRD). Here, we discuss a rare case of a patient with tumour calcification complicated with calciphylaxis developed septic shock from infection. Our patient is a 57-year...